Splice

2010 104 min ★ 5.9 Horror, Science Fiction

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

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Cast

Adrien Brody

Clive

Sarah Polley

Elsa

Delphine Chanéac

Dren

David Hewlett

Barlow

Abigail Chu

Young Dren

Stephanie Baird

Elsa / PD

Brandon McGibbon

Gavin

Amanda Brugel

Melinda Finch

Simona Măicănescu

Joan Chorot

Details

Director

Vincenzo Natali

Screenplay

Antoinette Terry Bryant

Tagline

"She's not human...not entirely."

Status

Released

Original Language

EN

Budget

$26,000,000

Production

Copperheart Entertainment, Gaumont, Senator Film, Dark Castle Entertainment

Reviews

A

Andres Gomez

November 26, 2014

★ 5/10

The FX is OK and the uneasiness and thrill is always there but the script is stereotypical, weak and full of holes.

J

John Chard

December 2, 2018

★ 6/10

Brundledren! Splice is a tricky picture to evaluate, for its ideas are superb. One could argue that it brings a new petri dish full of meddling scientists facing the consequences of their actions, while conversely it justifiably feels like a Cronenberg knock-off. Psychological discord is in abundance, with its slants on skew-whiff parenting giving the pic a dark fascination, and as unpleasan...

C

CinemaSerf

October 26, 2022

★ 5/10

"Clive" (Adrien Brody) and "Elsa" (Sarah Polley) are a couple of genetic engineers charged by David Hewlett's "Barlow" with discovering an important gene that could lead to huge advances in medical science. Using a mix of human and animal DNA that have varying degrees of success before the evolution of a creature "Dren" (Delphine Chanéac) that develops more human attributes - as well as a tail wit...